Methylenetetrahydrofolate Reductase (MTHFR) Antibody,Abbexa,abx011720

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Host

Mouse

Reactivity

Human, Rat

Application

ELISA, WB, IHC

Conjugate

Unconjugated

Platform ID

BAB208682068

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameMethylenetetrahydrofolate Reductase (MTHFR) Antibody
Cat. No.abx011720
Accession NumberP42898
Gene ID (Entrez)4524
HostMouse
IsotypeIgG1
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationELISA, WB, IHC
Working DilutionsELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
ConcentrationNot determined.
Molecular Weight75 kDa
ImmunogenPurified recombinant fragment of human MTHFR expressed in E. coli.
PurityUnpurified ascites.
Appearance/FormLiquid
FormulationAscitic fluid containing 0.03% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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