Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1) Antibody,Abbexa,abx033844

This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB, IHC

Conjugate

Unconjugated

Platform ID

BAB174709647

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Abbexa

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Email:

[email protected]

Product Specifications

Specifications

NameMitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1) Antibody
Cat. No.abx033844
Accession NumberO43683
Gene ID (Entrez)699
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB, IHC
Working DilutionsWB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 122 kDa
TargetBUB1
ImmunogenKLH-conjugated synthetic peptide between 1043-1073 amino acids from the C-terminal region of human BUB1 (BUB1a).
PurityPurified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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