Mouse IgG2aIsotype Control [Clone C1.18.4 (LALA-PG)] — Fc Muted™,Leinco,C582
Host
Mouse
Platform ID
BAB831930809
Leinco
Contact
Tel: +1 (800) 538-1145,+1 (636) 230-9477
Fax:
Email:
Product Specifications
Scientific Background
Specifications
NameMouse IgG2aIsotype Control [Clone C1.18.4 (LALA-PG)] — Fc Muted™
Cat. No.C582
HostMouse
Concentration≥ 5.0 mg/ml
Purity≥95% by SDS Page ⋅ ≥95% monomer by analytical SEC
Endotoxin Level≤ 1.0 EU/mg as determined by the LAL method
ShippingNext Day Ambient
FormulationThis recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
StorageFunctional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one year. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≥ -80°C. Avoid Repeated Freeze Thaw Cycles.
Scientific Background
In this Fc Muted™ format, mutations (LALA-PG) have been introduced at crucial binding sites of the Fc domain with the FcR and C1q, reducing or eliminating Fc-mediated Antibody Dependent Cellular Phagocytosis (ADCP).
Category Paths
- Products>Primary Antibodies>Isotype Controls
Request a product
Please provide the required information below so that we can quickly source your products.