Mouse Tensin-4 (TNS4) ELISA Kit,Abbkine,KTE70084
• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.
Platform ID
BAB456380126
Abbkine
Contact
Tel: +1-404-854-0155
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Specifications
Scientific Background
CTEN was reduced or lost in several prostate cancers and in prostate cancer cell lines.The deduced 715-amino acid protein has a calculated molecular mass of 76.9 kD. The C terminus of CTEN shares 50% and 45% amino acid identity with the C termini of tensin-1 and tensin-2, respectively. Like these proteins, CTEN contains Src homology-2 and phosphotyrosine-binding domains, but it lacks the N-terminal actin-binding domain. CTEN also has 6 potential tyrosine phosphorylation sites. Endogenous CTEN expressed by a nontransformed prostate epithelial cell line and CTEN synthesized by in vitro transcription and translation both had an apparent molecular mass of about 90 kD by SDS-PAGE. Immunofluorescence staining localized CTEN to focal adhesions in prostate epithelial cells.
Synonyms
TNS4; CTEN; FLJ14950; PP14434; C terminal tensin like; C-terminal tensin-like; OTTHUMP00000164465
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