Mouse Transmembrane inner ear expressed protein (TMIE) ELISA Kit,Abbkine,KTE70159
• Do not mix components from different kit lots or use reagents beyond the kit expiration date.• Allow all reagents to warm to room temperature for at least 30 minutes before opening.• Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination. • Unused wells must be kept desiccated at 4 °C in the sealed bag provided.• Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.• It is recommended that all samples and standards be assayed in duplicate or triplicate.
Platform ID
BAB885852731
Abbkine
Contact
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Specifications
Scientific Background
TMIE encodes a transmembrane inner ear protein. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment. TMIE gene is expressed in many human tissues and encodes a transcript of approximately 2.5 kb. Repeated RACE experiments on cDNA from human retina and various other tissues yielded an approximately 1.7-kb transcript; no other TMIE transcripts were identified. Sequence analysis predicted an intracellular N terminus, 2 transmembrane regions separated by an extracellular loop, and an intracellular C terminus.
Synonyms
TMIE; DFNB6; transmembrane inner ear protein
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