Mouse Txnip Antibody,Abbexa,abx031399
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
Host
Rabbit
Reactivity
Mouse
Application
ELISA, WB, IHC
Conjugate
Unconjugated
Platform ID
BAB024567726

Abbexa
Contact
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Product Specifications
Specifications
NameMouse Txnip Antibody
Cat. No.abx031399
Accession NumberQ8BG60
HostRabbit
IsotypeIgG
ReactivityMouse
ConjugationUnconjugated
ApplicationELISA, WB, IHC
Working DilutionsWB: 1/2000, IHC-P: 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 44.4 kDa
ImmunogenKLH-conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.
PurityPurified through a protein A column, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Polyclonal Antibodies
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