Myeloid Leukemia Factor 1 (MLF1) Antibody,Abbexa,abx217001
Myeloid Leukemia Factor 1 (MLF1) Antibody is a Rabbit Polyclonal antibody for the detection of MLF1. Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Application
ELISA, WB
Conjugate
Unconjugated
Platform ID
BAB204094156
Abbexa
Contact
Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951
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Product Specifications
Specifications
NameMyeloid Leukemia Factor 1 (MLF1) Antibody
Cat. No.abx217001
Accession NumberP58340
Gene ID (Entrez)4291
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationELISA, WB
Working DilutionsWB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Concentration2 mg/ml
Molecular WeightObserved MW: 38 kDa
TargetMLF1
Immunogenmyeloid leukemia factor 1
PurityPurified by immunogen affinity chromatography.
Appearance/FormLiquid
FormulationPBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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