NADPH oxidase 4 Polyclonal Antibody,Bioss,bs-4730R

Host

Rabbit

Reactivity

Human

Application

WB, ELISA, FCM

Conjugate

Unconjugated

Platform ID

BAB120573804

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNADPH oxidase 4 Polyclonal Antibody
Cat. No.bs-4730R
Accession NumberQ9NPH5
Gene ID (Entrez)50507
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, ELISA, FCM
Working DilutionsWB:1:300-5000 | ELISA:1:500-1000 | FCM:1:20-100
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.

Synonyms

Kidney oxidase-1; Kidney superoxide-producing NADPH oxidase; KOX 1; KOX; Kox-1; NADPH; NADPH oxidase 4; Nox4; NOX4_HUMAN; Renal NADPH-oxidase; RENOX.

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