NCK1 Recombinant Antibody,Bioss,bsm-54207r

Host

Rabbit

Application

WB, FCM, IHC-P, IF(IHC-P), IF(ICC)

Conjugate

Unconjugated

Platform ID

BAB354995021

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNCK1 Recombinant Antibody
Cat. No.bsm-54207r
Accession NumberP16333
Gene ID (Entrez)4690
HostRabbit
IsotypeIgG
ConjugationUnconjugated
ApplicationWB, FCM, IHC-P, IF(IHC-P), IF(ICC)
Working DilutionsWB:1:300-5000 | FCM:1:20-100 | IHC-P:1:200-400 | IF(IHC-P):1:50-200 | IF(ICC):1:50-200
ClonalityRecombinant
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageStore at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Scientific Background

Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.

Synonyms

Cytoplasmic protein NCK1; NCK adaptor protein 1; SH2/SH3 adaptor protein NCK-alpha; Nck-1; NCK1; NCK.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.