NCOR1 antibody,Genetex,GTX129621

Host

Rabbit

Reactivity

Human

Application

WB IP

Conjugate

Unconjugated

Platform ID

BAB840865830

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNCOR1 antibody
Cat. No.GTX129621
Gene ID (Entrez)9611
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IP
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetNCOR1
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NCOR1. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. [provided by RefSeq]

Synonyms

nuclear receptor corepressor 1 , N-CoR , N-CoR1 , PPP1R109 , TRAC1 , hN-CoR

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