NCR3 Rabbit mAb,ABclonal,A24295

Reactivity

Human

Application

WB, IF/ICC, FC (intra), ELISA

Conjugate

Unconjugated

Platform ID

BAB661650515

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

Tel:
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Product Specifications
Scientific Background
Synonyms

Specifications

NameNCR3 Rabbit mAb
Cat. No.A24295
Accession NumberO14931
Gene ID (Entrez)259197
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IF/ICC, FC (intra), ELISA
Working DilutionsWB:1:1000 - 1:2000 | IF/ICC:1:200 - 1:800 | FC (intra):1:500 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC60018
Molecular Weight30kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

Synonyms

NCR3; 1C7; CD337; LY117; MALS; NKp30; natural cytotoxicity triggering receptor 3

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