NECAB3 antibody,Genetex,GTX87171

The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

APBA2BP , EFCBP3 , NECAB3 , NIP1 , Nterminal EFhand calcium binding protein 3 , STIP3 , SYTIP2 , XB51 , dJ63M2.4 , dJ63M2.5 , N-terminal EF-hand calcium binding protein 3