NEK2 antibody,Genetex,GTX118735

Host

Rabbit

Reactivity

Human

Application

WB ICC/IF IHC-P

Conjugate

Unconjugated

Platform ID

BAB642227429

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNEK2 antibody
Cat. No.GTX118735
Gene ID (Entrez)4751
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityPolyclonal
Concentration1.47 mg/ml (Please refer to the vial label for the specific concentration.)
TargetNEK2
ImmunogenRecombinant protein corresponding to human NEK2.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Protein kinase that is involved in mitotic regulation. Integral component of the mitotic spindle-assembly checkpoint which is necessary for proper chromosome segregation during metaphase-anaphase transition. Required for association of MAD2L1 to kinetochore. Phosphorylates SGOL1. May have a role at the G2-M transition. May also play a role in meiosis. Isoform 1 but not isoform 2 appears to play a role in centrosome splitting. Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells. Isoform 2, which is not present in the nucleolus, does not.

Synonyms

NIMA related kinase 2 , HsPK21 , NEK2A , NLK1 , PPP1R111 , RP67

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.