NF-E2 antibody [N1C3],Genetex,GTX102698

Host

Rabbit

Reactivity

Human

Application

WB ICC/IF IP ChIP-seq

Conjugate

Unconjugated

Platform ID

BAB924947980

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNF-E2 antibody [N1C3]
Cat. No.GTX102698
Gene ID (Entrez)4778
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF IP ChIP-seq
ClonalityPolyclonal
Concentration0.32 mg/ml (Please refer to the vial label for the specific concentration.)
TargetNFE2
ImmunogenRecombinant protein encompassing a sequence within the center region of human NF-E2. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 1% BSA, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Synonyms

nuclear factor, erythroid 2 , NF-E2 , p45

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