NF-H antibody,Genetex,GTX85459

Host

Chicken

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IHC

Conjugate

Unconjugated

Platform ID

BAB137745788

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNF-H antibody
Cat. No.GTX85459
Gene ID (Entrez)4744
HostChicken
IsotypeIgY
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetNEFH
ImmunogenChickens were immunized with NF-H protein purified from adult bovine brains.
PurityIgY fraction
Appearance/FormLiquid
FormulationPBS, 1% BSA,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]

Synonyms

neurofilament heavy , CMT2CC , NFH

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