NF2 Antibody (YA1386),MedChemexpress,HY-P81641

NF2 Antibody (YA1386) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NF2.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB

Conjugate

Non-conjugated

Platform ID

BAB446258092

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

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Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameNF2 Antibody (YA1386)
Cat. No.HY-P81641
Accession NumberP35240
Gene ID (Entrez)4771
HostRabbit
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB
Working DilutionsWB: 1:1000-1:5000
ClonalityRecombinant,Monoclonal
Clone NumberYA1386
Molecular WeightPredicted band size: 70 kDa; Observed band size: 70 kDa
ImmunogenA synthetic peptide of human NF2/Merlin
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

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Scientific Background

The related gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of The protein's function has been implicated in tumorirelated genesis and metastasis. Mutations in The related gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities.

Synonyms

ACN; BANF; Merlin; Moesin ezrin radixin like protein; Neurofibromatosis 2; Neurofibromin 2; Nf2; SCH; Schwannomerlin

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