NFAT1 antibody [25A10.D6.D2],Genetex,GTX22722
Host
Mouse
Reactivity
Human, Mouse, Rat
Application
WB ICC/IF IHC-P IHC-Fr FCM IP ChIP assay Gel supershift assays
Conjugate
Unconjugated
Platform ID
BAB925936241

Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Specifications
Scientific Background
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.
Synonyms
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 , AI607462 , NF-ATc2 , NF-ATp , NFAT1 , NFAT1-D , Nfatp
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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