NFkB p65 (acetyl Lys310) antibody,Genetex,GTX86963

Host

Rabbit

Reactivity

Human, Mouse, Monkey

Application

WB ICC/IF IHC-P IHC

Conjugate

Unconjugated

Platform ID

BAB889020176

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameNFkB p65 (acetyl Lys310) antibody
Cat. No.GTX86963
Gene ID (Entrez)5970
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetRELA
ImmunogenThe antiserum was produced against synthesized peptide derived from human NFkB p65 (275-324).
PurityPurified by antigen-affinity chromatography. Non-acetylated peptide was removed by chromatography using corresponding non-acetylated peptide.From serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Synonyms

NFKB3 , RELA , RELA protooncogene, NFkB subunit , p65 , NFkB p65 , NF-κb p65 , v-rel avian reticuloendotheliosis viral oncogene homolog A

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