NFkB p65 (phospho Ser311) antibody,Genetex,GTX78995

Host

Rabbit

Reactivity

Human

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB368779896

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNFkB p65 (phospho Ser311) antibody
Cat. No.GTX78995
Gene ID (Entrez)5970
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetRELA
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human NFκB-p65 around the phosphorylation site of serine 311 (F-K-Sp-I-M).
PurityPurified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.From serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format),0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Synonyms

NFKB3,RELA,RELA protooncogene, NFkB subunit,p65,NFkB p65,NF-κb p65,RELA proto-oncogene, NF-kB subunit

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