NLRP7 antibody [N3C2], Internal,Genetex,GTX120931

Host

Rabbit

Reactivity

Human, Sheep

Application

WB ICC/IF IHC-P

Conjugate

Unconjugated

Platform ID

BAB458881684

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNLRP7 antibody [N3C2], Internal
Cat. No.GTX120931
Gene ID (Entrez)199713
HostRabbit
IsotypeIgG
ReactivityHuman, Sheep
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityPolyclonal
Concentration0.76 mg/ml (Please refer to the vial label for the specific concentration.)
TargetNLRP7
ImmunogenRecombinant protein encompassing a sequence within the center region of human NLRP7. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Synonyms

NLR family pyrin domain containing 7 , CLR19.4 , HYDM , NALP7 , NOD12 , PAN7 , PYPAF3

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