NMNAT1 antibody,Genetex,GTX66480

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB419566771

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNMNAT1 antibody
Cat. No.GTX66480
Gene ID (Entrez)64802
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetNMNAT1
ImmunogenRecombinant funsion protein containing a sequence corresponding to amino acids 1-150 of human NMNAT1 (NP_073624.2).
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15. [provided by RefSeq, Jul 2014]

Synonyms

nicotinamide nucleotide adenylyltransferase 1 , LCA9 , NMNAT , PNAT1

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