NSDHL (F3P8W) Rabbit Monoclonal Antibody#15356,Cell Signaling Technology (CST),15356

NAD(P) dependent steroid dehydrogenase-like (NSDHL) is an enzyme involved in the late stages of cholesterol biosynthesis (1). Mutations in theNSDHLgene are associated with the X-linked conditions CHILD (congenital hemidysplasia with ichthyosiform erythroderma and limb defects) and CK syndromes (2,3). Elevated NSDHL expression has been found in several cancer types, including breast, gastric, pancreatic, and multiple myeloma, and can be a potent driver of metastasis and predictor of poor prognosis (4-8). ÂLiu, X.Y. et al. (1999)Nat Genet22, 182-7.König, A. et al. (2000)Am J Med Genet90, 339-46.McLarren, K.W. et al. (2010)Am J Hum Genet87, 905-14.Gabitova-Cornell, L. et al. (2020)Cancer Cell38, 567-583.e11.Chen, M. et al. (2021)Breast Cancer Res Treat187, 349-362.Kang, W. et al. (2022)Am J Cancer Res12, 4566-4583.Zhao, N. et al. (2023)Sci Rep13, 19395.Yoon, S.H. et al. (2020)BMC Cancer20, 375.Alternate Namesepididymis secretory sperm binding protein; H105E3; NAD(P) dependent steroid dehydrogenase-like; NAD(P) dependent steroid dehydrogenase-like protein transcript; NSDHL; Protein H105e3; SDR31E1; short chain dehydrogenase/reductase family 31E, member 1; Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; XAP104

epididymis secretory sperm binding protein; H105E3; NAD(P) dependent steroid dehydrogenase-like; NAD(P) dependent steroid dehydrogenase-like protein transcript; NSDHL; Protein H105e3; SDR31E1; short chain dehydrogenase/reductase family 31E, member 1; Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; XAP104