NUMB antibody [1A7],Genetex,GTX83974

Host

Mouse

Reactivity

Human, Dog

Application

WB ICC/IF FCM

Conjugate

Unconjugated

Platform ID

BAB882323392

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNUMB antibody [1A7]
Cat. No.GTX83974
Gene ID (Entrez)8650
HostMouse
IsotypeIgG1
ReactivityHuman, Dog
ConjugationUnconjugated
ApplicationWB ICC/IF FCM
ClonalityMonoclonal
Concentration0.6 mg/ml (Please refer to the vial label for the specific concentration.)
TargetN
ImmunogenFull length human recombinant protein of human NUMB (NP_003735) produced in HEK293T cell.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Synonyms

NUMB endocytic adaptor protein , C14orf41 , S171 , c14_5527

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