Nephrin Rabbit pAb- ABclonal,ABclonal,A27762

Reactivity

Mouse, Rat

Application

WB, IF-F, IF-P, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB492797810

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNephrin Rabbit pAb- ABclonal
Cat. No.A27762
Accession NumberQ9QZS7
Gene ID (Entrez)54631
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB, IF-F, IF-P, IHC-P, ELISA
Working DilutionsWB:1:1500 - 1:3000 | IF-F:1:50 - 1:200 | IF-P:1:50 - 1:200 | IHC-P:2000-8000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight200kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.

Synonyms

CNF; NPHN; nephrin

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