Neurofilament L Rabbit pAb- ABclonal,ABclonal,A0257

Reactivity

Human, Mouse, Rat

Application

WB, IF-P, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB307752881

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

Tel:
Fax:

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNeurofilament L Rabbit pAb- ABclonal
Cat. No.A0257
Accession NumberP07196
Gene ID (Entrez)4747
RRIDAB_2757070
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF-P, IHC-P, ELISA
Working DilutionsWB:1:500 - 1:5000 | IF-P:1:50 - 1:200 | IHC-P:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight70 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Synonyms

NFL; NF-L; NF68; CMT1F; CMT2E; CMTDIG; PPP1R110; Neurofilament L

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