Non-L-Type Cav Channel Antibody Explorer Kit,Alomone Labs,AK-216_KIT

Voltage-dependent Ca 2+ channels (Ca v ) form an important route for Ca 2+ entry into cells, upon deviations from the cells’ resting membrane potential. There are ten Ca v α 1 subunit genes, divided into three subfamilies on both a functional and sequence homology basis. The Ca v 1 subfamily includes four genes which encode the L-type channels, the Ca v 3 subfamily includes three genes encoding the T-type channels and the Ca v 2 subfamily consists of three isoforms encoding P/Q- , N- and R-type channels, with all three contributing to neurotransmitter release in neurons.