Nuclear Mitotic Apparatus Protein 1 (NUMA1) Antibody,Abbexa,abx000744

NUMA1 Antibody is a Rabbit Polyclonal antibody against NUMA1. This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

ELISA, WB, IHC, IF/ICC

Conjugate

Unconjugated

Platform ID

BAB058897677

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameNuclear Mitotic Apparatus Protein 1 (NUMA1) Antibody
Cat. No.abx000744
Accession NumberQ14980
Gene ID (Entrez)4926
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationELISA, WB, IHC, IF/ICC
Working DilutionsELISA: 1 µg/ml, WB: 1/200 - 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Concentration2.58 mg/ml
Molecular WeightCalculated MW: 238 kDa Observed MW: 238 kDa
TargetNUMA1
ImmunogenRecombinant protein corresponding to NUMA1. The exact sequence is proprietary.
PurityPurified by affinity chromatography.
Appearance/FormLiquid
FormulationPBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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