Nucleophosmin Rabbit mAb,ABclonal,A27297
Reactivity
Human, Mouse, Rat
Application
WB, IHC-P, IF/ICC, ELISA
Conjugate
Unconjugated
Platform ID
BAB662050323

ABclonal
Contact
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Specifications
Scientific Background
The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified.
Synonyms
B23; NPM
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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