Nucleophosmin Rabbit mAb,ABclonal,A27297

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB662050323

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

NameNucleophosmin Rabbit mAb
Cat. No.A27297
Accession NumberP06748
Gene ID (Entrez)4869
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, ELISA
Working DilutionsWB:1:5000 - 1:30000 | IHC-P:1:2000 - 1:8000 | IF/ICC:1:200 - 1:800 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC73080
Molecular Weight38kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified.

Synonyms

B23; NPM

Category Paths

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