Nucleophosmin antibody [7H10B9],Genetex,GTX83217

Host

Mouse

Reactivity

Human, Monkey

Application

WB ICC/IF IHC-P ELISA

Conjugate

Unconjugated

Platform ID

BAB317293357

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameNucleophosmin antibody [7H10B9]
Cat. No.GTX83217
Gene ID (Entrez)4869
HostMouse
IsotypeIgG1
ReactivityHuman, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P ELISA
ClonalityMonoclonal
TargetNPM1
ImmunogenPurified recombinant fragment of human Nucleophosmin (2-265) expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]

Synonyms

nucleophosmin 1 , B23 , NPM

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