OATP2 antibody [ESL],Genetex,GTX15441

Host

Mouse

Reactivity

Human

Application

WB ICC/IF IP

Conjugate

Unconjugated

Platform ID

BAB727697648

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameOATP2 antibody [ESL]
Cat. No.GTX15441
Gene ID (Entrez)10599
HostMouse
IsotypeIgM
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF IP
ClonalityMonoclonal
TargetSLCO1B1
ImmunogenSynthetic peptide corresponding to residues E(671) S L N K N K H F V P S A G A D S E T H C(691) of human OATP2.
PurityUnpurified
Appearance/FormLiquid
FormulationTissue culture supernatant,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]

Synonyms

solute carrier organic anion transporter family member 1B1 , HBLRR , LST-1 , LST1 , OATP-C , OATP1B1 , OATP2 , OATPC , SLC21A6

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