OATP8 antibody, Internal,Genetex,GTX88295

Host

Goat

Reactivity

Human

Application

WB ICC/IF FCM

Conjugate

Unconjugated

Platform ID

BAB832536037

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameOATP8 antibody, Internal
Cat. No.GTX88295
Gene ID (Entrez)28234
HostGoat
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF FCM
ClonalityPolyclonal
Concentration0.50 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSLCO1B3
ImmunogenPeptide with sequence C-NGTSPEIVEKD, from the internal region of the protein sequence according to NP_062818.1.
PurityPurified by ammonium sulphate precipitation followed by antigen affinity chromatography
Appearance/FormLiquid
FormulationTBS, 0.5% BSA,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]

Synonyms

solute carrier organic anion transporter family member 1B3 , HBLRR , LST-2 , LST-3TM13 , LST3 , OATP-8 , OATP1B3 , OATP8 , SLC21A8

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