OCIAD1 antibody,Genetex,GTX85234

Host

Rabbit

Reactivity

Human

Application

WB ICC/IF ELISA

Conjugate

Unconjugated

Platform ID

BAB574115081

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameOCIAD1 antibody
Cat. No.GTX85234
Gene ID (Entrez)54940
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF ELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetOCIAD1
ImmunogenOCIAD1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human OCIAD1.The immunogen is located within the last 50 amino acids of OCIAD1.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

OCIAD1 was identified via immunoscreening of an ovarian carcinoma cDNA library from ovarian cancer patients and is expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland. Two isoforms of OCIAD1 are known to exist; the shorter isoform is restricted to the central nervous system. OCIAD1 is a transmembrane protein whose overexpression in HEY ovarian cancer cells increased lysophosphatidic acid- (LPA-)induced, but not basal level cell adhesion to extracellular matrix proteins collagen I and laminin10/11. This adhesion is not blocked by LY294002 and GF109203X, suggesting that OCIAD1 does not use protein kinase C and PI3 kinase signaling pathways to exert its effect on adhesion.

Synonyms

OCIA domain containing 1 , ASRIJ , OCIA , TPA018

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