OLR1 / LOX-1 antibody [23C11],Genetex,GTX54456

Host

Mouse

Reactivity

Human, Mouse

Application

ICC/IF IHC-P FCM Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB567329604

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameOLR1 / LOX-1 antibody [23C11]
Cat. No.GTX54456
Gene ID (Entrez)4973
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationICC/IF IHC-P FCM Neutralizing /Inhibition
ClonalityMonoclonal
Concentration100 μg/ml (Please refer to the vial label for the specific concentration.)
TargetOLR1
ImmunogenFusion protein of extracellular domain (aa 71-273) of human LOX-1 with murine Fcγ1 (LOX-1-muFc) produced in PEAK cells
PurityPurified IgG1
Appearance/FormLiquid
FormulationFilter-sterilized PBS, 0.1% BSA,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Synonyms

CLEC8A,LOX1,LOXIN,OLR1,SCARE1,SLOX1,oxidized low density lipoprotein receptor 1,LOX-1

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