OLR1 / LOX-1 antibody [B019M],Genetex,GTX39124

Host

Mouse

Reactivity

Human

Application

WB ELISA

Conjugate

Unconjugated

Platform ID

BAB710494645

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameOLR1 / LOX-1 antibody [B019M]
Cat. No.GTX39124
Gene ID (Entrez)4973
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ELISA
ClonalityMonoclonal
Concentration3.80 mg/ml (Please refer to the vial label for the specific concentration.)
TargetOLR1
ImmunogenRecombinant sLOX-1 expressed in E. coli.
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Synonyms

oxidized low density lipoprotein receptor 1 , CLEC8A , LOX1 , LOXIN , SCARE1 , SLOX1

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