Occludin antibody,Genetex,GTX114949

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Application

WB ICC/IF IHC-P IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB197162312

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameOccludin antibody
Cat. No.GTX114949
Gene ID (Entrez)100506658
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr
ClonalityPolyclonal
Concentration0.94 mg/ml (Please refer to the vial label for the specific concentration.)
TargetOCLN
ImmunogenRecombinant protein encompassing a sequence within the center region of human Occludin. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]

Synonyms

occludin , BLCPMG , PPP1R115 , PTORCH1

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