Orai1 antibody,Genetex,GTX54826

Host

Rabbit

Reactivity

Human

Application

WB ICC/IF FCM IHC

Conjugate

Unconjugated

Platform ID

BAB256722445

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameOrai1 antibody
Cat. No.GTX54826
Gene ID (Entrez)84876
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF FCM IHC
ClonalityPolyclonal
Concentration0.65 mg/ml (Please refer to the vial label for the specific concentration.)
TargetORAI1
ImmunogenPeptide (C)KKQPGQPRPTSK, corresponding to amino acid residues 203-214 (2nd extracellular loop) of human Orai1 (Accession : Q96D31).
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]

Synonyms

ORAI calcium release-activated calcium modulator 1 , CRACM1 , IMD9 , ORAT1 , TAM2 , TMEM142A

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