Origin Recognition Complex Subunit 6 (ORC6) Antibody,Abbexa,abx004156

ORC6 Antibody is a Rabbit Polyclonal antibody against ORC6. The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

ELISA, WB, IHC

Conjugate

Unconjugated

Platform ID

BAB830604551

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameOrigin Recognition Complex Subunit 6 (ORC6) Antibody
Cat. No.abx004156
Accession NumberQ9Y5N6
Gene ID (Entrez)23594
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationELISA, WB, IHC
Working DilutionsELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Concentration> 0.2 mg/ml
Molecular WeightCalculated MW: 28 kDa Observed MW: 28 kDa
TargetORC6
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human ORC6.
PurityPurified by affinity chromatography.
Appearance/FormLiquid
FormulationPBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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