Osteocalcin antibody [8H12F9H10],Genetex,GTX39498

Host

Mouse

Reactivity

Human, Rat, Rabbit, Bovine, Pig

Application

ELISA

Conjugate

Unconjugated

Platform ID

BAB773575616

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameOsteocalcin antibody [8H12F9H10]
Cat. No.GTX39498
Gene ID (Entrez)632
HostMouse
IsotypeIgG1
ReactivityHuman, Rat, Rabbit, Bovine, Pig
ConjugationUnconjugated
ApplicationELISA
ClonalityMonoclonal
Concentration1.0 mg/ml (Please refer to the vial label for the specific concentration.)
TargetBGLAP
ImmunogenRecombinant human osteocalcin GST fusion protein.
PurityProtein G purified
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]

Synonyms

bone gamma-carboxyglutamate protein , BGP , OC , OCN

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