PABP antibody [10E10],Genetex,GTX26125

Host

Mouse

Reactivity

Human, Rabbit, Chicken, Xenopus laevis

Application

WB ICC/IF IP ELISA

Conjugate

Unconjugated

Platform ID

BAB242440568

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePABP antibody [10E10]
Cat. No.GTX26125
Gene ID (Entrez)26986
HostMouse
IsotypeIgG2b
ReactivityHuman, Rabbit, Chicken, Xenopus laevis
ConjugationUnconjugated
ApplicationWB ICC/IF IP ELISA
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPABPC1
ImmunogenRecombinant PABP (Human) expressed from its 1.85 kbp cDNA, NcoI to SspI
PurityProtein A
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]

Synonyms

poly(A) binding protein cytoplasmic 1 , PAB1 , PABP , PABP1 , PABPC2 , PABPL1

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