PAI-1 antibody [3A120],Genetex,GTX40924

Host

Mouse

Reactivity

Human

Application

WB

Conjugate

Unconjugated

Platform ID

BAB088380759

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePAI-1 antibody [3A120]
Cat. No.GTX40924
Gene ID (Entrez)5054
HostMouse
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
ClonalityMonoclonal
Concentration5.52 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSERPINE1
ImmunogenRecombinant full length protein: human PAI
PurityProtein A purified
Appearance/FormLiquid
Formulation50mM Sodium Phosphate, 100mM NaCl,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Synonyms

serpin family E member 1 , PAI , PAI-1 , PAI1 , PLANH1

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