PAI-1 antibody,Genetex,GTX79738

Host

Rabbit

Reactivity

Human

Application

WB IHC-P IHC-Fr IP ELISA

Conjugate

Unconjugated

Platform ID

BAB245916370

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePAI-1 antibody
Cat. No.GTX79738
Gene ID (Entrez)5054
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P IHC-Fr IP ELISA
ClonalityPolyclonal
Concentration10 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSERPINE1
ImmunogenRecombinant full length wild-type human protein (Non-glycosylated).
PurityPurified by antigen-affinity chromatographyFrom serum
Appearance/FormLiquid
Formulation50mM Sodium Phosphate, 100mM NaCl, 1mM EDTA,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Synonyms

PAI,PAI1,PLANH1,SERPINE1,serpin family E member 1,PAI-1,Serpin E1

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