PAK2 antibody [3B5],Genetex,GTX83373

Host

Mouse

Reactivity

Human, Monkey

Application

WB ICC/IF IHC-P ELISA

Conjugate

Unconjugated

Platform ID

BAB193030503

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePAK2 antibody [3B5]
Cat. No.GTX83373
Gene ID (Entrez)5062
HostMouse
IsotypeIgG1
ReactivityHuman, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P ELISA
ClonalityMonoclonal
TargetPAK2
ImmunogenPurified recombinant fragment of PAK2(AA : 4-223) expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]

Synonyms

p21 (RAC1) activated kinase 2 , PAK65 , PAKgamma

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