PAK6 antibody,Genetex,GTX78145

Host

Rabbit

Reactivity

Human

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB180036743

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePAK6 antibody
Cat. No.GTX78145
Gene ID (Entrez)56924
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPAK6
ImmunogenSynthetic 19 amino acid peptide from Linker domain of human PAK6.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Synonyms

p21 (RAC1) activated kinase 6 , PAK5 , PAK6

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