PARP Recombinant Antibody,Bioss,bsm-52433r-TR

Host

Rabbit

Reactivity

Human, Mouse

Application

WB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC)

Conjugate

Unconjugated

Platform ID

BAB040489734

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePARP Recombinant Antibody
Cat. No.bsm-52433r-TR
Accession NumberP09874
Gene ID (Entrez)142
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC)
Working DilutionsWB:1:500-2000 | FCM:FCM1:50-100 | IHC-P:IHC-P1:100-500 | IHC-F:IHC-F1:100-500 | IF(IHC-P):IFIHC-P1:100-500 | IF(ICC):IFICC1:100-500
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageStore at -20°C for 12 months.

Scientific Background

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008].

Synonyms

Poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase diphtheria toxin-like 1, NAD(+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthase 1, PARP-1, ARTD1, ADPRT 1, PARP1

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