PARP (cleaved) antibody (FITC),Genetex,GTX24831

Host

Rabbit

Reactivity

Human, Mouse, Bovine

Application

WB ICC/IF FCM IHC

Conjugate

Fluorescein isothiocyanate (FITC) Wavelength

Platform ID

BAB303222643

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePARP (cleaved) antibody (FITC)
Cat. No.GTX24831
Gene ID (Entrez)142
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Bovine
ConjugationFluorescein isothiocyanate (FITC) Wavelength
ApplicationWB ICC/IF FCM IHC
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetPARP1
ImmunogenThe antiserum was produced against a chemically synthesized peptide corresponding to N-terminus of cleavage site (214/215) of human PARP.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, BSA,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

Synonyms

poly(ADP-ribose) polymerase 1 , ADPRT , ADPRT 1 , ADPRT1 , ARTD1 , PARP , PARP-1 , PPOL , pADPRT-1

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