PCSK9 antibody,Genetex,GTX129859

Host

Rabbit

Reactivity

Human, Rat

Application

WB FCM ELISA

Conjugate

Unconjugated

Platform ID

BAB966128204

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePCSK9 antibody
Cat. No.GTX129859
Gene ID (Entrez)255738
HostRabbit
IsotypeIgG
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB FCM ELISA
ClonalityPolyclonal
Concentration0.21 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPCSK9
ImmunogenRecombinant protein encompassing a sequence within the center region of human PCSK9. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 1% BSA, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq]

Synonyms

proprotein convertase subtilisin/kexin type 9 , FH3 , HCHOLA3 , LDLCQ1 , NARC-1 , NARC1 , PC9

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