PD1 antibody [9X21],Genetex,GTX52962

Host

Mouse

Reactivity

Human

Application

WB Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB373788755

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePD1 antibody [9X21]
Cat. No.GTX52962
Gene ID (Entrez)5133
HostMouse
IsotypeIgG2
ReactivityHuman
ConjugationUnconjugated
ApplicationWB Neutralizing /Inhibition
ClonalityMonoclonal
Concentration500 μg/ml (Please refer to the vial label for the specific concentration.)
TargetPDCD1
ImmunogenHuman recombinant PD-1
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Synonyms

CD279 , PD1 , PDCD1 , SLEB2 , hPD1 , hPDl , hSLE1 , programmed cell death 1 , PD-1

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