PDE4A (phospho Ser140) antibody,Genetex,GTX60930

Host

Rabbit

Reactivity

Human, Mouse, Rat, Rabbit

Application

WB IP ELISA

Conjugate

Unconjugated

Platform ID

BAB580523268

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePDE4A (phospho Ser140) antibody
Cat. No.GTX60930
Gene ID (Entrez)5141
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Rabbit
ConjugationUnconjugated
ApplicationWB IP ELISA
ClonalityPolyclonal
Concentration0.57 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPDE4A
ImmunogenSynthetic peptide corresponding to PKA phosphorylation site on PDE4A long form enzymes. The peptide was synthesized with phosphorylated serine residue.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationTris/Glycine, 0.5% BSA, 30% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Synonyms

phosphodiesterase 4A , DPDE2 , PDE4 , PDE46

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