PDE6D antibody,Genetex,GTX25665

Host

Rabbit

Reactivity

Human, Mouse, Sheep, Bovine

Application

WB ICC/IF IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB178959789

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NamePDE6D antibody
Cat. No.GTX25665
Gene ID (Entrez)5147
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Sheep, Bovine
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-Fr
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPDE6D
ImmunogenSynthetic Peptides: M(1) S A K D E R A R (D/E) I L R G F K(16) C
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS, 0.1% BSA,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014]

Synonyms

phosphodiesterase 6D , JBTS22 , PDED

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