PDE8B antibody,Genetex,GTX85801

Host

Rabbit

Reactivity

Human, Monkey

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB700876735

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NamePDE8B antibody
Cat. No.GTX85801
Gene ID (Entrez)8622
HostRabbit
IsotypeIgG
ReactivityHuman, Monkey
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.3 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPDE8B
ImmunogenSynthetic 16 amino acid peptide from internal region of human PDE8B.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]

Synonyms

phosphodiesterase 8B , ADSD , PDE8B , PPNAD3

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